This session will discuss research billing compliance is a critical facet of the healthcare landscape, playing a pivotal role in ensuring ethical and transparent financial practices within the realm of medical research. Our organization underwent an extensive research compliance review in 2014. Key observations indicated that research billing compliance processes and controls were highly variable across the program, and the hospital’s revenue cycle staff desired additional education and training on federal requirements as well as clarity on how study teams are ensuring the identification and flagging of research charges. In addition, gaps in policies and procedures existed, and organizational training and education on research billing compliance requirements were needed to drive awareness and accountability. A working group was created to address the recommendations of the audit. The outcomes of the success of this program have not previously been reported on. Here, I will present the findings of creating an efficient, harmonized process assigning accountability to the most appropriate owners and responsible parties to strike an appropriate balance between responsibilities to minimize error rates.