CAR-T and other cell therapies introduce a level of operational complexity that many organizations underestimate. From pre-award planning through final claim submission, success depends on decisions that must align across research, clinical operations, revenue cycle, and compliance.

Beginning with pre-award considerations, we will examine how early study decisions shape downstream coverage, documentation, and reimbursement. The discussion then moves into the mechanics of constructing defensible coverage analyses and translating those determinations into charge capture, coding logic, and billing practices that hold up under payer scrutiny.

Attendees will learn how to:

• Identify pre-award decisions that directly impact operational readiness
• Build coverage analyses that can be executed — not just approved
• Create charge structures that reflect clinical workflow and prevent manual rework
• Align coding and billing processes with coverage determinations
• Anticipate operational pressure points that lead to denials and delayed payment
• Establish documentation practices that support clean claims

Designed for professionals who already understand the fundamentals, this session emphasizes practical strategies organizations can implement immediately. Participants will leave with a clearer framework for supporting compliant claims, reducing downstream rework, and strengthening operational coordination across teams responsible for bringing these therapies from protocol to payment.